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蔡宗苇 兼职教授 主要从事质谱的基本原理及应用的研究

姓名:蔡宗苇

职称:兼职教授 博士生导师

 

【联系方式】

Email:zwcai@hkbu.edu.hk

 

【个人简历】

2010.1-至今 香港浸会大学,讲座教授

2005.1-2009.12 香港浸会大学,教授

2001.1-2005.5 香港浸会大学,副教授

1997.1-2001.1 美国格兰素-唯康药物公司,研究员

1994.7-1996.12 美国内布拉斯加大学,研究助理教授

1991.7-1996.6 美国内布拉斯加大学,博士后

1987.9-1990.12 德国马尔堡大学分析化学,理学博士

1978.9-1982.6 厦门大学化学专业,理学学士

 

【研究领域】

主要从事质谱的基本原理及应用;高分辨质谱;NanoESI质谱、气质、液质与毛细胞电泳质谱联用技术用于环境、生物、制药和中医药分析;毒物和持久性有机污染物的衡量分析等等。

先后承担过多项香港研究资助局优配研究基金和合作研究基金、香港环境与自然保育研究基金、香港卫生及医保服务研究基金、国家自然科学基金1项、国家自然科学基金(海外合作基金)等。多次参加国际会议并在会上发表口头报告。

 

【主要荣誉】

2011年获得国家自然科学奖二等奖;

2010 年获 Chemosphere(Elsevier)杂志“Top 50 most cited articles”in 2005-2010奖;

2006年,获得Journal of Chromatography (Elsevier) 杂志Top Cited Article 2001-2006奖;

2004年被中国科学院评为“海外知名学者”;

2003年获得国家自然科学杰出青年基金(海外、香港和澳门)。

 

【论文与专利】

1. Rongna Ma, Minghua Lu, Lin Ding, Huangxian Ju, Zongwei Cai, Surface-Assisted Laser Desorption/Ionization Mass Spectrometric Detection of Biomolecules by Using Functional Single-Walled Carbon Nanohorns as the Matrix, Chemistry-A European J., 2013, 19, 102-108.

2. Xiang Gao, Hanzhi Wu, Kim-Chung Lee, Hongxia Liu, Yufen Zhao, Zongwei Cai, Yuyang Jiang, Stable isotope N-phosphorylation labeling for peptide de novo sequencing and protein quantification based on organic phosphorus chemistry, Anal. Chem., 2012, 84, 10236 – 10244.

3. Xiang Gao, Zhi Tang, Minghua Lu, Hongxia Liu, Yuyang Jiang, Yufen Zhao, Zongwei Ca, Suppression of matrix ions by N-phosphorylation labeling using matrix-assisted laser desorption–ionization time-of-flight mass spectrometry, Chem. Commun., 2012, 48, 1 0198–10200.

4. Yanxia Li, Mei Hong, Yanqin Lin, Qiu Bin, Zhenyu Lin, Zongwei Cai, Guonan Chen, Highly sensitive electrochemical immunoassay for H1N1 influenza virus based on copper-mediated amplification, Chem. Commun., 2012,48, 6562-6564.

5. Chong He, Yiran Wu, Yongquan Lai, Zongwei Cai, Ying Liu, Luhua Lai, "Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network", Mol. BioSyst., 2012, 8, 1585-1594.

6. Yongning Wu, Yuxin Wang, Jingguang Li, Yunfeng Zhao, Feifei Guo, Jiaying Liu, Zongwei Cai, "Perfluorinated compounds in seafood from coastal areas in China", Environment International, 2012, 42, 67-71.

7. Yongquan Lai, Minghua Lu, Shuhai Lin, Zongwei Cai, "Glucuronidation of Hydroxylated Polybrominated Diphenyl Ethers and Their Modulation of Estrogen UDP-Glucuronosyltransferases", Chemosphere, 2012, 86, 727-734.

8. Jingguang Li, Feifei Guo, Yuxin Wang, Jiaying Liu, Zongwei Cai, Jialing Zhang, Yunfeng Zhao, Yongning Wu, "Development of extraction methods for the analysis of perfluorinated compounds in human hair and nail by high performance liquid chromatography tandem mass spectrometry", J. Chromatogr. A, 2012, 1219, 54-60.

9. Ning Liu, Lichun Zhao, Chengyan He, Zongwei Cai, "Advances in Technologies and Biological Applications of 18O Labeling Strategies in LC-MS Based Proteomics", An Updated Review, Current Anal. Chem., 2012, 8, 22-34.

10. Hongde Liu, Shuhai Lin, Zongwei Cai, Xiao Sun, "Role of 10-11 bp periodicities of eukaryotic DNA sequence in nucleosome positioning", Biosystems, 2011, 105, 295-299.

11. Yongquan Lai, Minghua Lu, Xiang Gao, Hanzhi Wu, Zongwei Cai, "New Evidence for Toxicity of Polybrominated Diphenyl Ethers: DNA Adducts Formation from Quinone Metabolites", Environ. Sci. Technol., 2011, 45, 10720-727.

12. Minghua Lu, Yongquan Lai, Guonan Chen, Zongwei Cai, "Laser desorption/ionization on the layer of graphene nanoparticles coupled with mass spectrometry for characterization of polymers", Chem. Commun., 2011, 47, 12807-12809.

13. Yongquan Lai, Minghua Lu, Shuhai Lin, Hanzhi Wu, Zongwei Cai, "Electrospray ionization tandem mass spectrometric characterization of DNA adducts formed by bromobenzoquinones", Rapid Commun. Mass Spectrom., 2011, 25, 2943-2950.

14. Shuhai Lin, Zhu Yang, Xiaojun Zhang, Zhaoxiang Bian, Zongwei Cai, "Hippocampal metabolomics reveals 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity associated with ageing in Sprague-Dawley rats", Talanta, 2011, 85, 1007-1012.

15. Han-Zhi Wu, Lin Guo, Yuen-Fun Mak, Ning Liu, Wing-Tat Poon, Yan-Wo Chan, Zongwei Cai, "Proteomics Investigation on Aristolochic Acid Nephropathy: A Case Study on Rat Kidney Tissue", Anal. Bioanal. Chem., 2011, 399, 3431-3439.

16. Yongquan Lai, Minghua Lu, Xiang Gao, Hanzhi Wu, Zongwei Cai, New evidence for toxicity of polybrominated diphenyl ethers: DNA adduct formation from quinone metabolites, Environ. Sci. Technol., 2011, 45, pp 10720–10727.

【兼职情况】

Talanta,Rapid Communication in Mass Spectrometry,Journal of Pharmaceutical and Biomedical,Analysis,《中国色谱杂志》、《环境化学》、《色谱》、《科学通报》等杂志编委。

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