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谭英 讲师 主要从事化学生物学研究

姓名:谭英

职称:讲师

所属学科:化学

 

联系方式】

电话:0755-26036533

E-mail:tan.ying@sz.tsinghua.edu.cn

办公地址:深圳市西丽大学城清华园区J栋402室

 

【个人简历】

2001年09月~2005年07月,华中师范大学应用化学专业本科毕业

2005年09月~2010年07月,华中师范大学/南开大学化学专业博士

2010年07月~2012年07月,清华大学博士后

2012年10月~至今,清华大学深圳研究生院生命与健康学部讲师

2016年10月~2017年10月,新加坡国立大学访问学者

  

【教学】

《生命分析化学》、《现代仪器分析与方法》

 

【研究领域】

  研究方向包括化学生物学、分子生物学、细胞生物学,围绕着化学分子与核酸、蛋白、多肽、细胞的相互作用;药物小分子的作用机制;生物信息学等领域展开研究。主持了国家自然基金、深圳市学科布局、深圳市基础研究等项目,参与了国家科技部重大专项、国家973、国家863等项目。

 

【研究成果】

[1] Pengcheng Xue, Shengnan He, Yu Mao, Long Qu, Feng Liu, Chunyan Tan, Yuyang Jiang, Ying Tan*. The Optimization and Characterization of an RNA-cleaving Fluorogenic DNAzyme Probe for MDA-MB-231 Cell Detection. Sensors, 2017, accepted.

[2] Kai Cai, Ying Tan, Chunyan Tan,* Jiatao Wu, Pan Wu, Jiamei Liang, Shuwen Liu, Bibo Zhang and Yuyang Jiang. An iminodiacetate-modified conjugated polyelectrolyte for fluorescent labeling of histidine-tagged proteins. Chem. Comm. 2017, accepted.

[3] Bibo Zhang, Haiyang Liu, Fengxu Wu, Gefei Hao, Yuzong Chen, Chunyan Tan*, Ying Tan*, Yuyang Jiang. A dual-response quinoline-based fluorescent sensor for the detection of Copper (II) and Iron(III) ions in aqueous medium. Sensors and Actuators B: Chemical. 2017, 243: 765-774.

[4] Yu Liu, Pan Wu, Jianhua Jiang, Jiatao Wu, Yan Chen, Ying Tan*, Chunyan Tan*, and Yuyang Jiang. Conjugated Polyelectrolyte Nanoparticles for Apoptotic Cell Imaging. ACS Applied Materials & Interfaces. 2016, 8: 21984-21989.

[5] Haiyang Liu, Bibo Zhanga, Chunyan Tana, Feng Liu, Jiakun Cao, Ying Tan* and Yuyang Jiang*. Simultaneous bioimaging recognition of Al3+ and Cu2+ in living-cell, and further detection of F and S2? by a simple fluorogenic benzimidazole-based chemosensor. Talanta. 2016, 161: 309-319.

[6] Haiyang Liu, Fengxu Wu, Bibo Zhang, Chunyan Tan, Yuzong Chen, Gefei Hao, Ying Tan* and Yuyang Jiang*. A simple quinoline-derived fluorescent sensor for the selective and sequential detection of copper(II) and sulfide ions and its application in living-cell imaging. RSC Advance, 2016, 6: 77508–77514.

[7] Chen, Z.; Wu, P.; Cong, R.; Xu, N.; Tan, Y.*; Tan, C*.; Jiang, Y., Sensitive Conjugated- Polymer-Based Fluorescent ATP Probes and Their Application in Cell Imaging. ACS Applied Materials & Interfaces. 2016, 8: 3567-3574.

[8] Haiyang Liu, Yunsheng Dong, Bibo Zhang, Feng Liua, Chunyan Tana, Ying Tan*, Yuyang Jiang. An efficient quinoline-based fluorescence sensor for zinc(II) and itsapplication in live-cell imaging. Sensors and Actuators B: Chemical. 2016, 234: 616–624.

[9] Ying Lv, Jiatao Wu, Pan Wu, Yu Zong Chen, Ying Tan,* Chunyan Tan* and Yuyang Jiang. A sensitive polymeric dark quencher-based sensing platform for fluorescence “turn on” detection of proteins. RSC Advance, 2016, 6: 42443–42446.

[10] Zheng Jing, Tan Chunyan, Xue Pengcheng, Cao Jiakun, Liu Feng, Tan Ying*, Jiang Yuyang, Proteolysis targeting peptide (PROTAP) strategy for protein ubiquitination and degradation. Biochem. Biophys. Res. Commun. 2016, 470(4): 936-940.

[11] Jiatao Wu, Chunyan Tan,* Zhifang Chen, Yu Zong Chen, Ying Tan* and Yuyang Jiang. Fluorescence array-based sensing of nitroaromatics using conjugated polyelectrolytes. Analyst. 2016, 141: 3242–3245.

[12] Changjun Chen, Haiyang Liu, Bin Zhang, Yanwei Wang, Kai Cai, Ying Tan*, Chunmei Gao*, Hongxia Liu, Chunyan Tan, Yuyang Jiang. A simple benzimidazole quinoline-conjugate fluorescent chemosensor for highly selective detection of Ag+. Tetrahedron. 2016, 72: 3980-3985.

[13] Li, L; Shen, W.; Zheng, J.; Lai, R.; Tan, C*.; Tan, Y.*; Jiang, Y. Mutation of the conserved GRG motif and decreasing activity of human RNase H2. Open Life Sci. 2015, 10, 322–327.

[14] Haiyang Liu, Xiaoshuang Li, Feng Liu, Ying Tan*, Yuyang Jiang*. A simple and novel amide ligand based on quinoline derivative used for palladium- catalyzed Suzuki coupling reaction. Journal of Organometallic Chemistry, 2015, 794: 27-32.

[15] Wu, Y.; Tan, Y.; Wu, J. T.; Chen, S. Y.; Chen, Y. Z.; Zhou, X. W.; Jiang, Y. Y.; Tan, C. Y. *, Fluorescence Array-Based Sensing of Metal Ions Using Conjugated Polyelectrolytes. ACS Applied Materials & Interfaces, 2015, 7: 6882-6888.

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