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叶大田 教授 主要从事生物医学工程研究

姓名:叶大田

职称:教授,博士生导师

职务:生物医学工程研究中心主任

 

【联系方式】

电话: 0755-26036386

传真: 0755-26036386

E-mail:yedt6386@sz.tsinghua.edu.cn,ydt-dea@tsinghua.edu.cn,

 

【个人简历】

1964年9月~1970年3月, 清华大学电机系工业企业电气化自动化专业本科毕业

1970年3月~1973年10月, 北京汽车制造厂动力分厂,技术员

1973年10月~1983年, 清华大学电机系应用电子学教研室助教

1983~1991年12月, 清华大学电机系生物医学工程教研室讲师

1988年10月~1990年7月, 英国曼彻斯特维多莉亚大学UMIST学院访问学者,并获硕士学位

1991年12月~1995年 8月, 清华大学电机系生物医学工程教研室副教授

1995年8月~至今 , 清华大学生物医学工程教授

1995年10月~2000年 清华大学电机系副系主任

1998年~至今 清华大学生物医学工程博士点的博士生导师

2000年10月-2004年7月 清华大学医学院党委副书记

2004年7月~至今 清华大学深圳研究生院生物医学工程研究中心主任

2007年11月 清华大学专业技术职称评定:2级教授

 

【研究领域】

研究方向:

1、生物医学信号与医学图像的检测、处理与模式识别

2、听觉神经生物学、听力检测、人工耳蜗与听力语言康复

3、生物医学测量传感器、数字化医疗仪器、医学微系统的研究开发

4、中医信息学研究

5、老年人、妇女儿童、残疾人保健康复工程

主持或参与的重大项目情况及成果:

主持和参与完成国家自然科学基金5项,国家科技支撑计划项目1项,北京市自然科学基金1项,广东省自然科学基金1项,深圳市科研基金3项,清华大学交叉学科研究基金项目2项,横向科研10多项。曾获得教育部科技进步奖和省部委科技进步奖多次,获得授权6项中国发明专利,发表学术论文100多篇,多次担任国际学术会议分会场主席。

 

【教学经历】

1.《信号与系统》

2.《数字信号处理》

3.《微机在生物医学工程中的应用》

4.《生物系统建墓与仿真》

5.培养的研究生已经获得硕士学位32人,获得博士学位8人。在校博士生9人,硕士生6人。

 

【主要荣誉】

1.多次获得“清华之友”优秀教师奖

2.1995年教育部科技进步二等奖

3.2000年清华大学“良师益友”奖

4.2003年教师节“教书育人奖”

5.2005年清华大学“良师益友”奖

 

【论文与专利】

专利成果:授权国家发明专利:6项

(1)“耳声发射听力检测仪及其测试方法”,中国发明专利99110838.8

(2)“基于心音分析的心脏病自动分类系统及其心音分段方法”,中国发明专利, ZL 200610060596.x

(3)“电子耳蜗听觉仿真平台、仿真试验方法及算法比较方法”,200610060579.6

(4)“电子耳蜗体外语音处理装置”,200610060580.9

(5)“电子耳蜗汉语声调的n度标记法的电刺激编码策略”,200610060582.8

(6)“一种具有S参数控制的基于汉语特征的电子耳蜗语音处理方法”, 200610060581.3

专著情况:《微机在生物医学工程中的应用》讲义上下册、机械工程手册部分章节、“医学成像原理原理”翻译

主要论文:(近三年)

[1]Weixiang Liu, Kehong Yuan, Datian Ye. “On alpha-Divergence based Nonnegative Matrix Factorization for Clustering Cancer Gene Expression Data”, Artificial Intelligence in Medicine, 2008,44(1):1-5. (IF:1.825)

[2]Jian Wu, Guangzhi Wang, Datian Ye, You Wang. A New System for Soft Tissue Balance Measurement in the Total Knee Replacement, IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2008 (In Press)

[3]Guan T, Gong Q, Ye DT*. A novel speech processing algorithm for cochlear implant based on selective fundamental frequency control. LECTURE NOTES IN COMPUTER SCIENCE, 2006, 4232: 272-279. (SCI: BFG80, Ei: 064510227553)

[4]吴剑,丁海曙,叶大田。用近红外脑组织血样仪评定保健食品康疲劳效果,光谱学与光谱分析,2008(In Press)

[5]Guan T, Gong Q, Ye DT*. Electric-stimulus rate encoding algorithm of Mandarin tonal information in cochlear implant. PROGRESS IN NATURAL SCIENCE, 2006, 16(12): 1315-1321. (SCI: 137DP, Ei: 070510400994)

[6]Weixiang Liu, Kehong Yuan, Jian Wu, Datian Ye*, et al. Combining Generalized NMF and Discriminative Mixture Models for Classification of Gene Expression Data, International Journal of Pattern Recognition and Artificial Intelligence, 2008,22(8):1-11. (IF:0.376)

[7]Weixiang Liu, Kehong Yuan, Sparse p-norm Nonnegative Matrix Factorization for Clustering Gene Expression Data, International Journal of Data Mining and Bioinformatics. 2008, 2(3):236-249

[8]Weixiang Liu, Kehong Yuan, Datian Ye*, Reducing Gene Expression Data via Nonnegative Matrix Factorization for Clustering Analysis, Journal of Biomedical Informatics, 2008,41(4): 602-606. (IF:2.0)

[9]Tian Guan, Qin Gong and Datian Ye*. Effective use of the spectral information in speech processing of cochlear implant. Progress in Natural Science. 2007, 17(3): 334-339

[10]Peng C, Qian X, Ye DT*. Electrogastrogram extraction using independent component analysis with references. NEURAL COMPUTING & APPLICATIONS. 2007, 16 (6): 581-587

[11]Guan Tian, Ye Datian*. Selective frequency amplitude modulation encoding strategy for cochlear implants(电子耳蜗的选择性频率幅度调制编码算法). Qinghua Daxue Xuebao/Journal of Tsinghua University(清华大学学报), 2006, 46(12): 2057-2060. (in Chinese, Ei: 070710427364)

[12]Li Lei, Kang Wei, Ye Datian*. A contact angle measurement method for the droplets in EWOD-based chips. Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007, 1071-1075.

[13]彭诚, 叶大田*. 小波变换模极大值重建方法消除胃电检测中的运动伪迹. 清华大学学报(自然科学版). 2007, 47(3): 428-431.

[14]Weixiang liu, Kehong Yuan, Guang Zhang, Shaowei Jia, Ping Xiao. Regularized Scatter Measure for linear Feature Extraction. The Second International Conference on Innovative Computing, Information and Control, Kumamoto, Japan. 2007: 4428262

[15]Weixiang Liu, Fei Peng, Shu Feng, Jiangsheng You, Ziqiang Chen, Jian Wu, Kehong Yuan, Datian Ye. Semantic Feature Extraction for Brain CT Image Clustering Using Nonnegative Matrix Factorization. Lecture Notes in Computer Science. 2008, 4901: 41-48

[16]Peng Cheng, Ye Datian*. Relative Power Percentage and Time-Power Percentages Map Analysis of Electrogastrogram Slow Waves. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.2:875-878

[17]李振明,傅新星,宫琴,叶大田*,刘博. 瞬态诱发耳声发射的功率谱定量指标应用于临床诊断. 清华大学学报(自然科学版),2008,48(6): 1053-1056

[18]郑燕娇,钱翔,周一平,张卫星,叶大田*. 基于单导肺音信号的呼吸气相识别. 清华大学学报. 2008, 48(12): 2136-2140

[19]李双双, 丁海艳, 侯新琳, 卞昕, 周丛乐, 叶大田*, 腾轶超. 振幅整合脑电及在新生猪缺氧脑损伤中的应用. 清华大学学报. 2008, 48(3): 423-427

[20]Jian WU, Ming ZHAO, Datian YE, Guangzhi Wang. A Method for widening the range of force measurement and gap adjustment in the Total Knee Replacement. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.1:802-805

[21]Jian wu. A Method for extracting 3D information of cylinder in C-arm image. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.2:544-547

[22]吴剑,叶大田,彭诚,钱翔,朱子俨,史小军,腾轶超。青藏铁路列员高海拔列车上的无创脑组织氧检测,清华大学学报(自然科学版),2008,(in press)

[23]彭诚, 刘博, 傅新星, 叶大田, 宫琴. 用瞬态诱发耳声发射信号识别听神经病的研究. 清华大学学报(自然科学版). 2009, 49(9) (in press)

[24]Qiuting Wen*, Jian Wu?, Hai Tao, Guangzhi Wang, Datian Ye*. An Approach to the Correspondence Problem in the 1-D Optical Transducers Tracking System, SPIE 2009, (in press)

[25]Zhang Dandan, Ding Haiyan, Hou Xinlin, Liu Yunfeng, Zhou Congle, Ye Datian*. The combination of amplitude and sample entropy in EEG and its application to assessment of cerebral injuries in piglets. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.2: 525-529

[26]腾轶超, 叶大田, 李岳, 黄岚, 吴先友, 丁海曙, 金国藩. 无损检测组织氧饱和度的近红外光学传感器的优化设计研究. 光谱学与光谱分析. 2008, 28(4): 953-957

[27]Guan T, Gong Q, Ye DT. A novel speech processing algorithm for cochlear implant based on selective fundamental frequency control. LECTURE NOTES IN COMPUTER SCIENCE, 2006, 4232: 272-279. (SCI: BFG80, Ei: 064510227553)

[28]吴剑,丁海曙,叶大田。用近红外脑组织血样仪评定保健食品康疲劳效果,光谱学与光谱分析,2008(In Press)

[29]Guan T, Gong Q, Ye DT. Electric-stimulus rate encoding algorithm of Mandarin tonal information in cochlear implant. PROGRESS IN NATURAL SCIENCE, 2006, 16(12): 1315-1321. (SCI: 137DP, Ei: 070510400994)

[30]Weixiang Liu, Kehong Yuan, Jian Wu, Datian Ye, et al. Combining Generalized NMF and Discriminative Mixture Models for Classification of Gene Expression Data, International Journal of Pattern Recognition and Artificial Intelligence, 2008,22(8):1-11. (IF:0.376)

[31]Weixiang Liu, Kehong Yuan, Sparse p-norm Nonnegative Matrix Factorization for Clustering Gene Expression Data, International Journal of Data Mining and Bioinformatics. 2008, 2(3):236-249

[32]Weixiang Liu, Kehong Yuan, Datian Ye, Reducing Gene Expression Data via Nonnegative Matrix Factorization for Clustering Analysis, Journal of Biomedical Informatics, 2008,41(4): 602-606. (IF:2.0)

[33]Tian Guan, Qin Gong and Datian Ye. Effective use of the spectral information in speech processing of cochlear implant. Progress in Natural Science. 2007, 17(3): 334-339

[34]Peng C, Qian X, Ye DT. Electrogastrogram extraction using independent component analysis with references. NEURAL COMPUTING & APPLICATIONS. 2007, 16 (6): 581-587

[35]Guan Tian, Ye Datian(关添, 叶大田). Selective frequency amplitude modulation encoding strategy for cochlear implants(电子耳蜗的选择性频率幅度调制编码算法). Qinghua Daxue Xuebao/Journal of Tsinghua University(清华大学学报), 2006, 46(12): 2057-2060. (in Chinese, Ei: 070710427364)

[36]Li Lei, Kang Wei, Ye Datian. A contact angle measurement method for the droplets in EWOD-based chips. Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007, 1071-1075.

[37]彭诚, 叶大田. 小波变换模极大值重建方法消除胃电检测中的运动伪迹. 清华大学学报(自然科学版). 2007, 47(3): 428-431.

[38]Weixiang liu, Kehong Yuan, Guang Zhang, Shaowei Jia, Ping Xiao. Regularized Scatter Measure for linear Feature Extraction. The Second International Conference on Innovative Computing, Information and Control, Kumamoto, Japan. 2007: 4428262

[39]Yuan Kehong, Liu Weixiang, Jia Shaowei, Xiao Ping, Bao Shanglian. Identifying the margin of glioma using 1H-MRSI data. The 1st International Conference on Bioinformatics and Biomedical Engineering(ICBBE2007), Wuhan, China. 2007: 1206-1209

[40]Weixiang Liu, Kehong Yuan,Zhenhua Xie. Sparse Nonnegative Matrix Factorization for Classification of Gene Expression Data. The 1st International Conference on Bioinformatics and Biomedical Engineering(ICBBE 2007), Wuhan, China. 2007: 180-183,

[41]Kehong Yuan, Weixiang Liu, Shaowei Jia, Ping Xiao. Fusion of MRI and DTI to Assist the Treatment Solution of Brian Tumor. The Second International Conference on Innovative Computing, Information and Control, Kumamoto, Japan. 2007: 4428261

[42]Weixiang Liu, Fei Peng, Shu Feng, Jiangsheng You, Ziqiang Chen, Jian Wu, Kehong Yuan, Datian Ye. Semantic Feature Extraction for Brain CT Image Clustering Using Nonnegative Matrix Factorization. Lecture Notes in Computer Science. 2008, 4901: 41-48

[43]Peng Cheng, Ye Datian. Relative Power Percentage and Time-Power Percentages Map Analysis of Electrogastrogram Slow Waves. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.2:875-878

[44]李振明,傅新星,宫琴,叶大田,刘博. 瞬态诱发耳声发射的功率谱定量指标应用于临床诊断. 清华大学学报(自然科学版),2008,48(6): 1053-1056

[45]郑燕娇,钱翔,周一平,张卫星,叶大田. 基于单导肺音信号的呼吸气相识别. 清华大学学报. 2008, 48(12): 2136-2140

[46]Nonnegative singular value decomposition for microarray data analysis of spermatogenesis. 5th Int. Conference on Information Technology and Applications in Biomedicine, ITAB 2008 in conjunction with 2nd Int. Symposium and Summer School on Biomedical and Health Engineering, IS3BHE 2008. Shenzhen, China. 2008:225-228

[47]李双双, 丁海艳, 侯新琳, 卞昕, 周丛乐, 叶大田, 腾轶超. 振幅整合脑电及在新生猪缺氧脑损伤中的应用. 清华大学学报. 2008, 48(3): 423-427

[48]Jian WU, Ming ZHAO, Datian YE, Guangzhi Wang. A Method for widening the range of force measurement and gap adjustment in the Total Knee Replacement. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.1:802-805

[49]Shu Feng, Kehong Yuan, Datian Ye, Efficient fitting range for scatter measurement with optical coherence tomography, The 7th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2008) ( In press)

[50]吴剑,叶大田,彭诚,钱翔,朱子俨,史小军,腾轶超。青藏铁路列员高海拔列车上的无创脑组织氧检测,清华大学学报(自然科学版),2008,(in press)

[51]彭诚, 刘博, 傅新星, 叶大田, 宫琴. 用瞬态诱发耳声发射信号识别听神经病的研究. 清华大学学报(自然科学版). 2009, 49(9) (in press)

[52]Zhang Dandan, Ding Haiyan, Hou Xinlin, Liu Yunfeng, Zhou Congle, Ye Datian*. The combination of amplitude and sample entropy in EEG and its application to assessment of cerebral injuries in piglets. 2008 International Conference on Biomedical Engineering and Informatics (BMEI2008), Sanya, China.2008, v.2: 525-529

[53]腾轶超, 叶大田, 李岳, 黄岚, 吴先友, 丁海曙, 金国藩. 无损检测组织氧饱和度的近红外光学传感器的优化设计研究. 光谱学与光谱分析. 2008, 28(4): 953-957

 

【兼职情况】

1.中国电子学会高级会员,生命电子学会专业委员会副主任委员

2.中国生物医学工程学会高级会员

3.中国仪器仪表学会高级会员

4.《航天医学与医学工程杂志》编委会委员

5.美国电器电子学会高级会员

6.国家自然科学基金评审专家

7.教育部科技成果奖评审专家

8.深圳市生物医学工程学会副理事长学术兼职:

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