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何永红 研究员 从事医学光学技术应用等领域研究

 

姓名:何永红

职称:教授(博士生导师)

职务:光学检测与成像实验室主任

 

【联系方式】

清华大学深圳研究生院光学检测与成像实验室

广东省深圳市南山区西丽大学城清华校区D楼302A

邮编PC: 518055

TEL: +86-755-26036873

FAX: +86-755-26036395

Email: heyh@sz.tsinghua.edu.cn

 

【个人简历】

主要教育经历、工作经历:

2004-现在,清华大学深圳研究生院光学检测与成像实验室,先后任讲师、副教授、教授(主任)。

2002-2004,英国Cranfield大学生命科学技术研究所博士后、Research Fellow。

1996-2002,华南师范大学激光生命科学研究所(国家重点学科),攻读并获光学硕士、博士学位。

1989-1994,就读于安徽医科大学卫生事业管理学院,获医学学士学位。

 

【研究领域】

多年从事光学方法、技术、仪器开发及其在生物医学中应用交叉学科科研工作,主持国家自然科学基金(6项)、国家863高技术研究发展计划、省市科技计划、企业科技开发等项目十多项。先后开展表面等离体共振(SPR)传感及成像技术、光学相干层析(OCT)技术、生物组织光学特性控制研究、光学声学结合的生物组织成像及肿瘤成像诊断方法等研究工作。

在SPR领域,围绕提高灵敏度和提高检测通量两个主题研究光学SPR检测方法、技术与应用,分别开拓了对称波导结构的长程SPR分析技术、偏振干涉调制SPR传感技术和线扫描SPR光谱成像技术,将折射率分辨率提高到2x10-8RIU。在OCT领域,实现仪器技术攻关并产业化;同时,发展了差分吸收OCT技术测量眼房水中糖浓度。针对血流检测多普勒OCT对入射角度的依赖,实现基于相关和OCT测量流体速度分布的新方法,消除入射角影响等。通过以上工作发表论文100多篇其中 SCI 收录50多篇(被他引200多次)、EI 收录50多篇;授权中国专利15项;共培养研究生30多名;获广东省科学技术一、三等奖各1项;所研发的技术被制定成国家标准2项。

 

【主要荣誉】

2007年广东省省级南粤优秀教师奖1项;

2008年清华大学校级优秀工作者1项;

2010年深圳市杰出青年基金获得者;

2011年教育部新世纪优秀人才获得者。

 

【论文与专利】

近三年发表的部分代表性论文(责任通信作者)如下:

1. Xinyuan Chong, Le Liu, Zhiyi Liu, Suihua Ma, Jun Guo, Yanhong Ji and Yonghong He*, Detect the hybridization of single-stranded DNA by parallel scan spectral surface plasmon resonance imaging, Plasmonics, DOI 10.1007/s11468-013-9530, 2013

2. Le Liu, Xiangliang Chen, Zhiyi Liu, Suihua Ma, Chan Du, Yonghong He*, Polarization Interference Interrogation of Angular Surface Plasmon Resonance Sensors with Wide Metal Film Thickness Tolerance, Sensors & Actuators: B. Chemical, 173: 218–224, ( 2012)

3. Zhiyi Liu, Le Liu, Xiaoxiao Wang, Heng Shi, Xinyuan Chong, Suihua Ma, Yanhong Ji, Jihua Guo, Hui Ma, Yonghong He*, Polarization Interferometry Based Wavelength-Interrogation Surface Plasmon Resonance Imager for Analysis of Microarrays, Journal of Biomedical Optics, 17: 036002 (2012)

4. Sunan Deng, Le Liu, Zhiyi Liu, Zhiyuan Shen, Guohua Li, Yonghong He*, Line-scanning Raman Imaging Spectroscopy for Detection of Fingerprints, Applied Optics, 51: 3701-3706, ( 2012).

5. Le Liu, Jingyu Xi, Zenghua Wu, Wenguang Zhang, Haipeng Zhou, Weibin Li, and Yonghong He, Online Spectroscopic Study on the Positive and the Negative Electrolytes in Vanadium Redox Flow Batteries, Journal of Spectroscopy, 2013: 453980,(2012)

6. Zhiyi Liu, Le Liu, Xinyuan Chong, Suihua Ma, Yanhong Ji, Jihua Guo, Hui Ma, Yonghong He*, Parallel-scan based microarray imager capable of simultaneous Surface Plasmon Resonance and hyperspectral fluorescence imaging, Biosensors and Bioelectronics, 30:180-187, 2011

7. Yong Zhou, Ye Hu, Nan Zeng, Yanhong Ji, Xiangsong Dai, Peng Li, Hui Ma, and Yonghong He*, Noninvasive monitoring of Pirenoxine Sodium concentration in aqueous humor based on dual-wavelength iris imaging technique, Biomedical Optics Express, Vol. 2 Issue 2, pp.231-242 , 2011

8. Zhiyi Liu, Le Liu, Xinyuan Chong, Jun Guo, Suihua Ma, Yanhong Ji, Hui Ma, Yonghong He*, Line-Monitoring, Hyperspectral Fluorescence Setup for Simultaneous Multi-Analyte Biosensing, Sensors, 11:10038-10047, 2011

9. Yong Zhou, Nan Zeng, Yanhong Ji, Yao Li, Xiangsong Dai, Peng Li, Lian Duan, Hui Ma, and Yonghong He*, Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in anterior chamber, Journal of Biomedical Optics, 16(1) 015004: 1-7, 2011.

10. Le Liu, Suihua Ma, Yanhong Ji, Zhiyi Liu, Xinyuan Chong, Yonghong He*, and Jihua Guo, A two-dimensional polarization interferometry based parallel scan angular surface plasmon resonance biosensor, Review of Scientific Instruments, 82(2): 023109, 2011

11. Zhiyuan Shen, Min Wang, Yanhong Ji, Yonghong He*, Xiangsong Dai, Peng Li, Hui Ma, Transverse flow velocity quantification using optical coherence tomography with correlation, Laser Physics Letters, 8(4):318-324, 2011.

12. Bolin Hu, Nan Zeng, Zhiyi Liu, Yanhong Ji, Weidong Xie, Qing Peng, Yong Zhou, Yonghong He*, Hui Ma, Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization Journal of Biomedical Optics, 16(1) 016003: 1-7, 2011.

13. Zhiyi Liu, Yonghong He*, Le Liu, Suihua Ma, Xinyuan Chong, Zhaoxu Hu, Hui Ma, Jihua Guo, Two-channel, quasi-confocal parallel scan fluorescence imaging for detection of biochips, Optics and Lasers in Engineering, 48(9): 849-855(2010)

14. Zhiyi Liu, Suihua Ma, Yanhong Ji, Le Liu, Zhaoxu Hu, Jihua Guo, Hui Ma, and Yonghong He*, Quasi-Confocal, Multichannel Parallel Scan Hyperspectral Fluorescence Imaging Method Optimized for Analysis of Multicolor Microarrays, ANALYTICAL CHEMISTRY, 82: 7752–7757(2010)

15. Le Liu, Zhaoxu Hu, Suihua Ma, Ying Zhang Yonghong He* and Jihua Guo, Detection of methane by a surface plasmon resonance sensor based on polarization interferometry and angle modulation, Optics and Lasers in Engineering, 48(12):1182-1185(2010)

 

 

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